Real Care for Real Patients
We earn our reputation as a top community-based laboratory every day by delivering fast, accurate test results that providers and patients can trust.
Jillene Kogan, MD, PhDMedical Director of Cytogenetics
The personal touch is what sets us apart. At ACL we personally engage with our clinician partners every day, so in this sense we function like a small local lab. However, we also see a large case volume, which gives us the experience of a large regional laboratory.
Clinical Service Areas
- Clinical Chemistry
- Coagulation
- Cytogenetics
- Cytology
- Diagnostic Immunology
- Endocrinology
- Hematology
- Histology
- Immunohematology
- Immunohistochemistry
- Microbiology
- Molecular Diagnostics
- Mycology
- Parasitology
- Serology
- Transfusion Medicine
Highlights of Clinical Services:
Cytogenetics
Cytogenetics provides high quality chromosome analyses for all types of samples including peripheral blood, amniotic fluid, chorionic villus (CVS), products of conception, skin biopsies, bone marrow, lymph nodes, and solid tumors. Traditional cytogenetics techniques as well as molecular cytogenetics analyses by Fluorescence in Situ Hybridization (FISH) are offered. We also culture fibroblasts and amniocytes for send-out testing or long-term storage.
See our complete list of cytogenetic FISH tests here.
Oncology
Certain cytogenetic abnormalities occur in cancers which may provide prognostic implications and assist in therapeutic decision-making. We offer chromosome analysis and FISH testing on bone marrow samples for leukemias and lymphomas. Blood chromosome analysis is available when bone marrow is unattainable and the blast count is greater than 10%. Chromosome analysis and FISH testing on solid tumors is also available.
FISH testing allows for the identification of certain chromosome abnormalities specific to different cancers. FISH is beneficial for detecting abnormalities which may not be visible by traditional chromosome analysis, or may be present at a low level. FISH testing may be ordered individually or as part of a panel specific to the patient's cancer type.
Prenatal
Chromosome abnormalities may be detected prenatally, which allow the couple to make decisions and plans with as much knowledge as possible. We offer chromosome analysis on both amniotic fluid and CVS. FISH testing for the most common aneuplodies are available for rapid results for both amniotic fluid samples and CVS.
Chromosome abnormalities are a common cause of miscarriage, some of which may be recurrent in a family. Chromosome analysis is available for products of conception. FISH testing for the common aneuploidies can be performed for samples that fail to grow in culture. FISH analysis is also available to confirm triplody in suspected partial hydatidiform moles.
Constitutional
Blood chromosome analysis is available for conditions such as developmental delay, birth defects, and recurrent miscarriage. FISH testing is also available for the more common microdeletion syndromes. FISH technology is useful when a specific condition is suspected, particularly when the size of the chromosomal abnormality is below the resolution of karyotyping.Chromosomal microarray is a new technology we offer for detecting chromosome abnormalities at unprecedented resolution, potentially down to the level of a single gene. SNP-based microarray is the highest resolution microarray which interrogates the entire genome for copy number changes for identification of both known and novel genomic disorders.